Examinando 7.1 Incentivos para publicaciones indizadas por Fecha de asunto

Publicación

Sistema de control adaptivo para pacientes con Diabetes Mellitus Tipo 1

(Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica, 2004)

Ríos Ríos, Buenaventura

;

Mesías Rodríguez, Walter

El objeto de estudio del presente Libro es entender y controlar la diabetes mellitus Tipo 1, haciendo uso de la teoría de estado y los algoritmos de control de los filtros Kalman, En algunos países del norte está adquiriendo características realmente epidémicas. Todas las personas mayores de 40 años, con ascendientes diabéticos, con exceso de peso o que beben demasiado licor, tienen tendencia a adquirir la enfermedad. De hecho, la diabetes es causante directa o indirectamente del incremento de la tasa de mortalidad en el país, y de la existencia de un gran número de personas invidentes o inválidas. En el Perú, existen aproximadamente un millón de diabéticos, de los cuales el 50% desconoce que padece la enfermedad y se estima que, unos de cada 20 diabéticos sufren de diabetes mellitus Tipo 1, también conocida como diabetes juvenil o insulino dependiente. Frente a ella, los científicos del mundo están desarrollando diversas tecnologías con el fin de aliviar la enfermedad con resultados diversos, dada su aplicabilidad práctica, son los de mayor uso desde hace algunas décadas. Dado que, teórica y experimentalmente, se conoce la ecuación matemática diferencial que relaciona a las variables insulina y glucosa en el organismo humano, es posible integrar estas funciones de medición, control y actuador, en un solo dispositivo electrónico implantable y programable PIMS (Programmable Implantable Medication System)

Publicación

Phenolic profiles of andean mashua (Tropaeolum tuberosum Ruíz & Pavón) tubers: Identification by HPLC-DAD and evaluation of their antioxidant activity

(Elsevier Ltd, 2008)

Chirinos R.

;

Campos D.

;

Costa N.

;

Arbizu C.

;

Pedreschi R.

;

Larondelle Y.

Qualitative high performance liquid chromatography with diode array detection (HPLC-DAD) was performed to characterize nonanthocyanin phenolic compounds in three different coloured mashua genotypes. The ORAC antioxidant activity contribution in the tubers related to the type of phenolic compounds present was also evaluated. Phenolic compounds were analysed by separating them into four main fractions: fraction I obtained by means of a liquid–liquid partition with ethyl acetate and fractions II, III and IV obtained by elution on a Sephadex LH-20 column. Fraction I revealed the presence of gallic acid, gallocatechin, procyanidin B2 and epigallocatechin. Other phenolic compounds such as hydroxycinnamic and hydroxybenzoic acid derivatives, rutin and/or myricetin derivatives were also present in fraction I. Fraction II was mainly composed of epicatechin, hydroxycinnamic and hydroxybenzoic acid derivatives. Fraction III presented mainly anthocyanins for the purple coloured mashua tubers and rutin, hydroxycinnamic acid and hydroxybenzoic acid derivatives for the yellow coloured genotype. Fraction IV was composed of proanthocyanidins. Alkaline and acid hydrolysis of the different fractions revealed the presence of gallocatechin, epicatechin, p-coumaric acid, o-coumaric acid, cinnamic acid, protocatechuic acid, rutin and quercetin as the main phenolic moieties present. The proanthocyanidin fractions were the major contributors to the ORAC antioxidant activity of the mashua tubers for two of the three genotypes (34.7–39.2%). The results obtained in the present study confirm that mashua tubers constitute a promising source of antioxidant phenolics and could potentially be considered as a functional food with beneficial health effects.

Publicación

Preliminary results from the MINERvA experiment

(Sissa Medialab Srl, 2011)

Harris D.A.

;

MINERvA1 Collaboration

The MINERvA experiment, operating since 2009 in the NuMI neutrino beam line at Fermilab, has collected neutrino and antineutrino scattering data on a variety of nuclear targets. The detector is designed to identify events originating in plastic scintillator, lead, carbon, iron, water, and liquid helium. The goal of the experiment is to measure inclusive and exclusive cross sections for neutrino and antineutrino with much greater precision than previous experiments. We present preliminary kinematic distributions for charged current quasi-elastic scattering and other processes. © Copyright owned by the author(s) under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike Licence.

Publicación

Arachne-A web-based event viewer for MINERvA

(Elsevier B.V., 2012)

Tagg, N

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Brangham, J

;

Chvojka, J

;

Clairemont, M

;

Day, M

;

Eberly, B

;

Felix, J

;

Fields, L

;

Gago, AM

;

Gran, R

;

Harris, DA

;

Kordosky, M

;

Lee, H

;

Maggi, G

;

Maher, E

;

Mann, WA

;

Marshall, CM

;

McFarland, KS

;

McGowan, AM

;

Mislivec, A

;

Mousseau, J

;

Osmanov, B

;

Osta, J

;

Paolone, V

;

Perdue, G

;

Ransome, RD

;

Ray, H

;

Schellman, H

;

Schmitz, DW

;

Simon, C

;

Salinas, CJS

;

Tice, BG

;

Walding, J

;

Walton, T

;

Wolcott, J

;

Zhang, D

;

Ziemer, BP

Neutrino interaction events in the detector are visually represented with a web-based tool called Arachne. Data are retrieved from a central server via AJAX, and client-side JavaScript draws images into the user's browser window using the draft HTML 5 standard. These technologies allow neutrino interactions to be viewed by anyone with a web browser, allowing for easy hand-scanning of particle interactions. Arachne has been used in to evaluate neutrino data in a prototype detector, to tune reconstruction algorithms, and for public outreach and education.

Publicación

The Design and Performance of the MINERνA Experiment

(Elsevier, 2012)

Budd H.S.

The design of the MINERνA detector is presented. We give an overview of the detector. We describe the optical system, giving details on the scintillator, the optical cabling and fibers, the PMTs, and the PMT housing. We give details on the electronics. We describe the assembled component, called the module, which gets inserted into the detector. We give details on the quality control of the modules and present documentation showing the performance of the detector

Publicación

Arachne-A web-based event viewer for MINERνA

(Elsevier B.V., 2012)

Tagg N.

;

Brangham J.

;

Chvojka J.

;

Clairemont M.

;

Day M.

;

Eberly B.

;

Felix J.

;

Fields L.

;

Gago A.M.

;

Gran R.

;

Harris D.A.

;

Kordosky M.

;

Lee H.

;

Maggi G.

;

Maher E.

;

Mann W.A.

;

Marshall C.M.

;

McFarland K.S.

;

McGowan A.M.

;

Mislivec A.

;

Mousseau J.

;

Osmanov B.

;

Osta J.

;

Paolone V.

;

Perdue G.

;

Ransome R.D.

;

Ray H.

;

Schellman H.

;

Schmitz D.W.

;

Simon C.

;

Solano Salinas C.J.

;

Tice B.G.

;

Walding J.

;

Walton T.

;

Wolcott J.

;

Zhang D.

;

Ziemer B.P.

Neutrino interaction events in the MINERνA detector are visually represented with a web-based tool called Arachne. Data are retrieved from a central server via AJAX, and client-side JavaScript draws images into the users browser window using the draft HTML 5 "standard". These technologies allow neutrino interactions to be viewed by anyone with a web browser, allowing for easy hand-scanning of particle interactions. Arachne has been used in MINERνA to evaluate neutrino data in a prototype detector, to tune reconstruction algorithms, and for public outreach and education. © 2012 Published by Elsevier B.V.

Publicación

Demonstration of communication using neutrinos

(World Scientific Publishing Co. Pte Ltd, 2012)

Stancil, DD

;

Adamson, P

;

Alania, M

;

Aliaga, L

;

Andrews, M

;

Del Castillo, CA

;

Bagby, L

;

Alba, JLB

;

Bodek, A

;

Boehnlein, D

;

Bradford, R

;

Brooks, WK

;

Budd, H

;

Butkevich, A

;

Caicedo, DAM

;

Capista, DP

;

Castromonte, CM

;

Chamorro, A

;

Charlton, E

;

Christy, ME

;

Chvojka, J

;

Conrow, PD

;

Danko, I

;

Day, M

;

Devan, J

;

Downey, JM

;

Dytman, SA

;

Eberly, B

;

Fein, JR

;

Felix, J

;

Fields, L

;

Fiorentini, GA

;

Gago, AM

;

Gallagher, H

;

Gran, R

;

Grange, J

;

Griffin, J

;

Griffin, T

;

Hahn, E

;

Harris, DA

;

Higuera, A

;

Hobbs, JA

;

Hoffman, CM

;

Hughes, BL

;

Hurtado, K

;

Judd, A

;

Kafka, T

;

Kephart, K

;

Kilmer, J

;

Kordosky, M

;

Kulagin, SA

;

Kuznetsov, VA

;

Lanari, M

;

Le, T

;

Lee, H

;

Loiacono, L

;

Maggi, G

;

Maher, E

;

Manly, S

;

Mann, WA

;

Marshall, CM

;

Mcfarland, KS

;

Mislivec, A

;

Mcgowan, AM

;

Morfin, JG

;

Da Motta, H

;

Mousseau, J

;

Nelson, JK

;

Niemiec-Gielata, JA

;

Ochoa, N

;

Osmanov, B

;

Osta, J

;

Palomino, JL

;

Paradis, JS

;

Paolone, V

;

Park, J

;

Pena, C

;

Perdue, G

;

Lara, CEP

;

Peterman, AM

;

Pla-Dalmau, A

;

Pollock, B

;

Prokoshin, F

;

Ransome, RD

;

Ray, H

;

Reyhan, M

;

Rubinov, P

;

Ruggiero, D

;

Sands, OS

;

Schellman, H

;

Schmitz, DW

;

Schulte, EC

;

Simon, C

;

Salinas, CJS

;

Stefanski, R

;

Stevens, RG

;

Tagg, N

;

Takhistov, V

;

Tice, BG

;

Tilden, RN

;

Velasquez, JP

;

Vergalosova, I

;

Voirin, J

;

Walding, J

;

Walker, BJ

;

Walton, T

;

Wolcott, J

;

Wytock, TP

;

Zavala, G

;

Zhang, D

;

Zhu, LY

;

Ziemer, BP

Beams of neutrinos have been proposed as a vehicle for communications under unusual circumstances, such as direct point-to-point global communication, communication with submarines, secure communications and interstellar communication. We report on the performance of a low-rate communications link established using the NuMI beam line and the MINERvA detector at Fermilab. The link achieved a decoded data rate of 0.1 bits/sec with a bit error rate of 1% over a distance of 1.035 km, including 240 m of earth.

Publicación

Phenolic compounds from Andean mashua (Tropaeolum tuberosum) tubers display protection against soybean oil oxidation

(SAGE, 2012)

Betalleluz-Pallardel I.

;

Chirinos R.

;

Rogez H.

;

Pedreschi R.

;

Campos D.

Phenolic compounds from mashua tuber were evaluated as potential antioxidants to retard the oxidation of crude soybean oil submitted to accelerated storage and frying. During the accelerated storage, an ethanolic crude extract, a purified extract, an aqueous fraction and an ethyl acetate fraction from mashua containing different gallic acid equivalent concentrations (100, 300 and 600 ppm) in oil were evaluated at 55 C. After 15 days of storage, better effects were evidenced against soybean oil oxidation at 300 and 600 ppm of ethyl acetate fraction in comparison to 200 ppm butylated hydroxytoluene and the control (no antioxidant added). During the frying process at 180 C, principal component analysis revealed that the content of trienes and dienes were strongly correlated with the frying batch. Ethyl acetate fraction at 200 ppm showed the highest efficacy against oil oxidation in terms of polar compound values, free fatty acids and conjugated dienes and trienes in comparison to the oil containing 200 ppm tert-butylhydroquinone and control. Differential scanning calorimetry corroborated the efficacy of ethyl acetate fraction phenolic and it is strongly recommended as method for validation of results. This study provides strong evidence related to the excellent protective effects against soybean oil oxidation of mashua phenolics. This crop could be utilized as an alternative source of natural antioxidants by the oil industry

Publicación

The influence of geographic heterogeneity in predation pressure on sexual signal divergence in an Amazonian frog species complex

(Oxford University Press, 2013)

Trillo, PA

;

Athanas, KA

;

Goldhill, DH

;

Hoke, KL

;

Funk, WC

Sexual selection plays an important role in mating signal divergence, but geographic variation in ecological factors can also contribute to divergent signal evolution. We tested the hypothesis that geographic heterogeneity in predation causes divergent selection on advertisement call complexity within the Engystomops petersi (previously Physalaemus petersi) frog species complex. We conducted predator phonotaxis experiments at two sites where female choice is consistent with call trait divergence. Engystomops at one site produces complex calls, whereas the closely related species at the other site produces simple calls. Bats approached complex calls more than simple calls at both sites, suggesting selection against complex calls. Moreover, bat predation pressure was greater at the site with simple calls, suggesting stronger selection against complex calls and potentially precluding evolution of complex calls at this site. Our results show that geographic variation in predation may play an important role in the evolution and maintenance of mating signal divergence.

Publicación

Oxfendazole flukicidal activity in pigs

(Elsevier, 2014)

Ortiz P.

;

Terrones S.

;

Cabrera M.

;

Hoban C.

;

Ceballos L.

;

Moreno L.

;

Canton C.

;

Donadeu M.

;

Lanusse C.

;

Alvarez L.

Although oxfendazole (OFZ) is a well know broad-spectrum benzimidazole anthelmintic, the assessment of its potential trematodicidal activity remains unexplored. OFZ administration at single high doses has been recommended to control Taenia solium cysticercus in pigs. The current study investigated the flukicidal activity obtained after a single high (30 mg/kg) oral dose of OFZ in pigs harbouring a natural Fasciola hepatica infection. Sixteen (16) local ecotype pigs were randomly allocated into two (2) experimental groups of 8 animals each named as follow: Untreated control and OFZ treated, in which animals received OFZ (Synanthic®, Merial Ltd., 9.06% suspension) orally at 30 mg/kg. At seven (7) days post-treatment, all the animals were sacrificed and direct adult liver fluke counts were performed following the WAAVP guidelines. None of the animals involved in this experiment showed any adverse event during the study. OFZ treatment as a single 30 mg/kg oral dose showed a 100% efficacy against F. hepatica. In conclusion, the trial described here demonstrated an excellent OFZ activity against F. hepatica in naturally infected pigs, after its administration at a single oral dose of 30 mg/kg.

Publicación

Determination of the threshold of nanoparticle behavior: Structural and electronic properties study of nano-sized copper

(Elsevier B.V., 2014)

Torres-Vega J.J.

;

Medrano L.R.

;

Landauro C.V.

;

Rojas-Tapia J.

In the present work we determine the threshold of the nanoparticle behavior of copper nanoparticles by studying their structural and electronic properties. The studied nanoparticles contain from 13 to 8217 atoms and were obtained by molecular dynamics simulations using the Johnson potential for copper based on the embedded atom method. The results indicate that for small copper nanoparticles (o1000 atoms, 2.8 nm) the surface plays an important role in their physical properties. Whereas, for large nanoparticles (42000 atoms, 3.5 nm), with spherical-like external shape and large percentage of fcc-like local structure, this effect is negligible and their electronic character are similar to such expected in solid copper. Finally, it has also been shown that copper nanoparticles change their electronic character, from metallic to insulating, after increasing the strength of the chemical disorder.

Publicación

Implementation of an alternative method to determine the critical cooling rate: Application in silver and copper nanoparticles

(Elsevier, 2014)

Medrano L.R.

;

Landauro C.V.

;

Rojas-Tapia J.

An alternative method to determine the critical cooling rate of materials has been developed by explaining the size and cooling rate dependences of physical properties of metallic nanoparticles through the scaling theory. This method has been applied to silver and copper nanoparticles which have been obtained by molecular dynamics simulations. The results reveal that our values for critical rate are close for each studied physical quantity. Thus, by taking the average among them, we obtain 6.2(8) × 1012 K/s for silver and 8.9(5) × 1012 K/s for copper. We have also found the threshold size of nanoparticle behavior is independent of the cooling rate.

Publicación

Design, calibration, and performance of the MINERvA detector

(Pontificia Universidad Católica del Perú, 2014)

Aliaga L.

;

Bagby L.

;

Baldin B.

;

Baumbaugh A.

;

Bodek A.

;

Bradford R.

;

Brooks W.K.

;

Boehnlein D.

;

Boyd S.

;

Budd H.

;

Butkevich A.

;

Martinez Caicedo D.A.

;

Castromonte C.M.

;

Christy M.E.

;

Chvojka J.

;

Da Motta H.

;

Damiani D.S.

;

Danko I.

;

Datta M.

;

Devan J.

;

Draeger E.

;

Dytman S.A.

;

Díaz G.A.

;

Eberly B.

;

Edmondson D.A.

;

Felix J.

;

Fields L.

;

Fiorentini G.A.

;

Flight R.S.

;

Gago A.M.

;

Gallagher H.

;

George C.A.

;

Gielata J.A.

;

Gingu C.

;

Gran R.

;

Grange J.

;

Grossman N.

;

Harris D.A.

;

Heaton J.

;

Higuera A.

;

Hobbs J.A.

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Howley I.J.

;

Hurtado K.

;

Jerkins M.

;

Kafka T.

;

Kantner M.O.

;

Keppel C.

;

Kilmer J.

;

Kordosky M.

;

Krajeski A.H.

;

Kumbartzki G.J.

;

Lee H.

;

Leister A.G.

;

Locke G.

;

Maggi G.

;

Maher E.

;

Manly S.

;

Mann W.A.

;

Marshall C.M.

;

McFarland K.S.

;

McGivern C.L.

;

McGowan A.M.

;

Mislivec A.

;

Morfín J.G.

;

Mousseau J.

;

Naples D.

;

Nelson J.K.

;

Niculescu G.

;

Niculescu I.

;

O'Connor C.D.

;

Ochoa N.

;

Olsen J.

;

Osmanov B.

;

Osta J.

;

Palomino J.L.

;

Paolone V.

;

Park J.

;

Perdue G.N.

;

Peña C.

;

Pla-Dalmau A.

;

Rakotondravohitra L.

;

Ransome R.D.

;

Ray H.

;

Ren L.

;

Rubinov P.

;

Rude C.

;

Sassin K.E.

;

Schellman H.

;

Schmitz D.W.

;

Schneider R.M.

;

Schulte E.C.

;

Simon C.

;

Snider F.D.

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Snyder M.C.

;

Solano Salinas C.J.

;

Tagg N.

;

Tice B.G.

;

Tilden R.N.

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Velásquez J.P.

;

Walton T.

;

Westerberg A.

;

Wolcott J.

;

Wolthuis B.A.

;

Woodward N.

;

Wytock T.

;

Zavala G.

;

Zeng H.B.

;

Zhang D.

;

Zhu L.Y.

;

Ziemer B.P.

The skin is the largest organ of the body that protects it from the external environment. High- frequency ultra sound (HF-US) has been used to visualize the skin in depth and to diagnose some pathologies in dermatological applications. Quantitative ultrasound (QUS) includes several techniques that provide values of particular physical properties. In this thesis work, three QUS parameters are explained and used to characterize healthy skin through HF-US: attenuation coefficient slope (ACS), backscatter coefficient (BSC) and shear wave speed (SWS). They were estimated with the regularized spectral-log difference (RSLD) method, the reference phan- tom method, and the crawling wave sonoelastography method, respectively. All the three parameters were assessed in phantoms, ex vivo and in vivo skin. In calibrated phantoms, RSLD showed a reduc- tion of up to 93% of the standard deviation concerning the estimation with SLD, and BSC showed an agreement with the Faran’s theoretical curve. In gelatin-based phantoms, surface acoustic waves (SAWs) were estimated in two interfaces: solid-water and solid-US gel, which all owed corroborating SAWs presence and finding an empirical compensation factor when the coupling interface is US gel. A correction factor of 0:97 for SAW-to-shear was found to avoid underestimation in phantoms. Porcine thigh was calculated in the range from 8 to 27 MHz, where the ACS was 4:08 _+_0:43 dB cm -1 MHz-1 and BSC was in the range from 10 1 to 10° sr-1 _cm-1. Crawling wave sonoelastography method was applied for the vibration frequencies between 200 Hz and 800 Hz, where SWS was in the range from 4:6 m/sto9:1 m/s. In vivo ACS and BSC were assessed in the healthy forearm and thigh, whereas SWS only in the thigh. The average ACS in the forearm dermis was 2.07dB cm-1 _MHz-1, which is in close agreement with the literature. A significant difference (p < 0.05) was found between the ACS in the forearm dermis and the thigh dermis (average ACS of 2.54dB cm-1 _MHz-1). The BSC of the forearm and thigh dermis were in the range from 10 -1 to 10° sr-1 _cm-1, and in the range from 10-1 to 10° sr-1 _cm-1, respectively. The SWS in the thigh dermis was 2:4 _+_0:38 m/s for a vibration frequency of 200Hz, with an increasing trend as frequency increases. Results suggest that these QUS parameters have the potential to be used as a tool for in vivo skin characterization and show potential for future application in skin lesions.

Publicación

MINERvA neutrino detector response measured with test beam data

(Elsevier, 2015)

Aliaga L.

;

Altinok O.

;

Araujo Del Castillo C.

;

Bagby L.

;

Bellantoni L.

;

Bergan W.F.

;

Bodek A.

;

Bradford R.

;

Bravar A.

;

Budd H.

;

Butkevich A.

;

Martinez Caicedo D.A.

;

Carneiro M.F.

;

Christy M.E.

;

Chvojka J.

;

Da Motta H.

;

Devan J.

;

Díaz G.A.

;

Dytman S.A.

;

Eberly B.

;

Felix J.

;

Fields L.

;

Fine R.

;

Flight R.

;

Gago A.M.

;

Gingu C.

;

Golan T.

;

Gomez A.

;

Gran R.

;

Harris D.A.

;

Higuera A.

;

Howley I.J.

;

Hurtado K.

;

Kleykamp J.

;

Kordosky M.

;

Lanari M.

;

Le T.

;

Leister A.J.

;

Lovlein A.

;

Maher E.

;

Mann W.A.

;

Marshall C.M.

;

McFarland K.S.

;

McGivern C.L.

;

McGowan A.M.

;

Messerly B.

;

Miller J.

;

Miller W.

;

Mislivec A.

;

Morfín J.G.

;

Mousseau J.

;

Muhlbeier T.

;

Naples D.

;

Nelson J.K.

;

Norrick A.

;

Ochoa N.

;

O'Connor C.D.

;

Osmanov B.

;

Osta J.

;

Paolone V.

;

Patrick C.E.

;

Patrick L.

;

Perdue G.N.

;

Pérez Lara C.E.

;

Rakotondravohitra L.

;

Ray H.

;

Ren L.

;

Rodrigues P.A.

;

Rubinov P.

;

Rude C.R.

;

Ruterbories D.

;

Schellman H.

;

Schmitz D.W.

;

Solano Salinas C.J.

;

Tagg N.

;

Tice B.G.

;

Urrutia Z.

;

Valencia E.

;

Walton T.

;

Westerberg A.

;

Wolcott J.

;

Woodward N.

;

Wospakrik M.

;

Zavala G.

;

Zhang D.

;

Ziemer B.P.

The MINERvA collaboration operated a scaled-down replica of thesolid scintillator tracking and sampling calorimeter regions of the MINERvA detector in a hadron test beam at the Fermilab Test Beam Facility. This paper reports measurements with samples of protons, pions, and electrons from 0.35 to 2.0 GeV/c momentum. The calorimetric response to protons, pions, and electrons is obtained from these data. A measurement of the parameter in Birks' law and an estimate of the tracking efficiency are extracted from the proton sample. Overall the data are well described by a Geant4-based Monte Carlo simulation of the detector and particle interactions with agreements better than 4% for the calorimetric response, though some features of the data are not precisely modeled. These measurements are used to tune the MINERvA detector simulation and evaluate systematic uncertainties in support of the MINERvA neutrino crosssection measurement program.

Publicación

Neutrino interactions on nuclei at MINERvA

(Editrice Compositori s.r.l., 2015)

Carneiro, MF

Here we present analysis results from the MINERvA experiment for scattering of neutrinos on nucleus in an energy region of few GeV. These results cover a plethora of processes important for high precision neutrino oscillation measurements in which recent results have suggested that the currently used models are insufficient.

Publicación

Measurement of muon plus proton final states in nu(mu) interactions on hydrocarbon at < E-nu >=4.2 GeV

(American Physical Society, 2015)

Walton, T

;

Betancourt, M

;

Aliaga, L

;

Altinok, O

;

Bodek, A

;

Bravar, A

;

Budd, H

;

Bustamante, MJ

;

Butkevich, A

;

Caicedo, DAM

;

Carneiro, MF

;

Castromonte, CM

;

Christy, ME

;

Chvojka, J

;

da Motta, H

;

Datta, M

;

Devan, J

;

Dytman, SA

;

Diaz, GA

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Eberly, B

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Felix, J

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Fields, L

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Fine, R

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Fiorentini, GA

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Gago, AM

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Gallagher, H

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Gran, R

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Harris, DA

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Higuera, A

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Hurtado, K

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Kleykamp, J

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Kordosky, M

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Kulagin, SA

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Le, T

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Maher, E

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Manly, S

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Mann, WA

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Marshall, CM

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Mari, CM

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McFarland, KS

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McGivern, CL

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McGowan, AM

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Messerly, B

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Miller, J

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Mislivec, A

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Morfin, JG

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Mousseau, J

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Muhlbeier, T

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Naples, D

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Nelson, JK

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Norrick, A

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Osta, J

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Paolone, V

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Park, J

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Patrick, CE

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Perdue, GN

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Rakotondravohitra, L

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Ransome, RD

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Ray, H

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Ren, L

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Rodrigues, PA

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Ruterbories, D

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Schellman, H

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Schmitz, DW

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Simon, C

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Snider, FD

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Sobczyk, JT

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Salinas, CJS

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Tagg, N

;

Tice, BG

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Valencia, E

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Wolcott, J

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Wospakrik, M

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Zavala, G

;

Zhang, D

;

Ziemer, BP

A study of charged-current muon neutrino scattering on hydrocarbon (CH) in which the final state includes a muon, at least one proton, and no pions is presented. Although this signature has the topology of neutrino quasielastic scattering from neutrons, the event sample contains contributions from quasielastic and inelastic processes where pions are absorbed in the nucleus. The analysis accepts events with muon production angles up to 70◦ and proton kinetic energies greater than 110 MeV. The cross section, when based completely on hadronic kinematics, is well-described by a relativistic Fermi gas nuclear model including the neutrino event generator modeling for inelastic processes and particle transportation through the nucleus. This is in contrast to the quasielastic cross section based on muon kinematics, which is best described by an extended model that incorporates multi-nucleon correlations. This measurement guides the formulation of a complete description of neutrino-nucleus interactions that encompasses the hadronic as well as the leptonic aspects of this process.

Publicación

Single neutral pion production by charged-current ν-μ interactions on hydrocarbon at 〈Eν〉=3.6 GeV

(Elsevier, 2015)

Le T.

;

Palomino J.L.

;

Aliaga L.

;

Altinok O.

;

Bercellie A.

;

Bodek A.

;

Bravar A.

;

Brooks W.K.

;

Butkevich A.

;

Martinez Caicedo D.A.

;

Carneiro M.F.

;

Christy M.E.

;

Chvojka J.

;

da Motta H.

;

Devan J.

;

Dytman S.A.

;

Díaz G.A.

;

Eberly B.

;

Felix J.

;

Fields L.

;

Fine R.

;

Gago A.M.

;

Gallagher H.

;

Gran R.

;

Harris D.A.

;

Higuera A.

;

Hurtado K.

;

Kordosky M.

;

Maher E.

;

Manly S.

;

Mann W.A.

;

Marshall C.M.

;

McFarland K.S.

;

McGivern C.L.

;

McGowan A.M.

;

Miller J.

;

Morfín J.G.

;

Mousseau J.

;

Nelson J.K.

;

Norrick A.

;

Osta J.

;

Paolone V.

;

Park J.

;

Patrick C.E.

;

Perdue G.N.

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Rakotondravohitra L.

;

Ransome R.D.

;

Ray H.

;

Ren L.

;

Rodrigues P.A.

;

Ruterbories D.

;

Schellman H.

;

Schmitz D.W.

;

Sobczyk J.T.

;

Solano Salinas C.J.

;

Tagg N.

;

Tice B.G.

;

Valencia E.

;

Walton T.

;

Wolcott J.

;

Yepes-Ramirez H.

;

Zavala G.

;

Zhang D.

;

Ziemer B.P.

Single neutral pion production via muon antineutrino charged-current interactions in plastic scintillator (CH) is studied using the MINERvA detector exposed to the NuMI low-energy, wideband antineutrino beam at Fermilab. Measurement of this process constrains models of neutral pion production in nuclei, which is important because the neutral-current analog is a background for appearance oscillation experiments. The differential cross sections for momentum and production angle, for events with a single observed and no charged pions, are presented and compared to model predictions. These results comprise the first measurement of the kinematics for this process.

Publicación

Fascioliasis in schoolchildren in the inter andean valley of Cajamarca, Peru

(WAAVP 2015, 2015-08)

Rodríguez Ulloa, Claudia Rivera-Jacinto, Marco Hobán Vergara, Cristian Del Valle Mendoza, Juana Mercedes Ortiz Oblitas, Pedro

Fascioliasis, caused by Fasciola hepatica, is a public health problem in Peru, especially in schoolchildren. Prevalence rates in livestock are over 80% in dairy cattle reared in the Andean valley of Cajamarca, Peru. The present investigation aimed to determine the prevalence of F. hepatica infection in schoolchildren and the main risk factors involved in its presentation. Two hundred and seventy schoolchildren nine years old and over from primary public institutions from the district of Los Baños del Inca (Cajamarca) were included in the investigation. Questionnaires were applied to parents and children and fecal samples were taken and evaluated using the rapid sedimentation technique. Blood samples were also collected and analyzed. Seventeen fecal samples were positive to F. hepatica eggs, giving a prevalence of 6.3% (95% CI 3.21 - 9.38). Significant differences were found with origin of the child, history of intestinal parasitism, and the habit of chewing grass (p< 0.05). The rural origin (OR 4.8, 95% CI: 1.53-15.08) and the habit of chewing grass (OR 3.26, CI: 95% 1.07 - 9.96) were the most likely risk factors associated with the acquisition of infection. The leukocyte count of infected children varied between 3900 and 10580 cells /mm3 (mean ± SD = 6458.3 ± 2080.3). Thirty three percent of children positive to F. hepatica eggs presented eosinophilia. We conclude that the prevalence of human fascioliasis in the district of Los Baños del Inca is at the mesoendemic level and rurality provides conditions for acquiring the infection.

Publicación

Molecular Phylogenetics and Taxonomy of the Andean Genus Lynchius Hedges, Duellman, and Heinicke 2008 (Anura: Craugastoridae)

(The Herpetologists' League, 2016)

Motta, AP

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Chaparro, JC

;

Pombal, JP

;

Guayasamin, JM

;

De la Riva, I

;

Padial, JM

We infer species relationships within Lynchius, a frog genus with four species distributed along the paramos and cloud forests of the Andes of northern Peru and southern Ecuador, and assess species diversity in light of comparative analyses of anatomical traits and inferred relationships. Phylogenetic analyses rely on ~7000 base pairs of mtDNA and nuDNA sequences aligned using similarity-alignment and treealignment and optimized under maximum likelihood and parsimony criteria. Inferred relationships place Lynchius as the sister group of the widespread genus Oreobates and this clade as the sister group of the high Andean genus Phrynopus. Our analyses corroborate the dissimilar species Lynchius simmonsi as part of this clade and place it as the sister group of the remaining species of Lynchius. Parsimony and maximum likelihood analyses differ in the internal relationships of Lynchius with respect to the placement of L. flavomaculatus, L. nebulanastes, and L. parkeri, but support the existence of two unnamed species. External morphological comparisons provide diagnostic characters for the two new species, which are named and described herein. Lynchius tabaconas is sister to L. flavomaculatus and occurs at ~2800 m in the cloud forests of Santuario Nacional Tabaconas-Namballe, Cajamarca, Peru. Lynchius oblitus occurs in the same area but at a higher elevation (~3300 m) and is sister to a clade formed by L. flavomaculatus and L. tabaconas in parsimony analyses and to L. nebulanastes in maximum likelihood analyses. We provide a new diagnosis for each of the six species and for the genus, as well as some natural history notes.

Publicación

CD133 in breast cancer cells and in breast cancer stem cells as another target for immunotherapy

(Permanyer Publications, 2016)

Tume, L

;

Paco, K

;

Ubidia-Incio, R

;

Moya, J

Breast cancer consists of a heterogeneous group of tumors with different features, biology and treatments. Cancer stem cells (CSCs) have been associated with an aggressive cellular behavior, resistance to chemotherapy and radiotherapy in many types of neoplasms, and a strong correlation between prominin-1 (CD133) expression in cancer stem cells from different types of cancer exist. A discussion is presented on recent immunotherapeutic strategies that target CD133 in breast CSCs. Furthermore, it is suggested that immunotherapy targeting CD133 breast CSCs and/or in combination with other current treatments result in a better outcome. © 2016 Sociedad Mexicana de Oncología.

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