5.1 Proyectos de Innovación y transferencia tecnológica
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PublicaciónIsolation and characterization of a fibrinogen-clotting enzyme from venom of the snake, Lachesis muta muta(Peruvian bushmaster)(Elsevier, 1989)
;Yarleque A. ;Campos S. ;Escobar E. ;Lazo F. ;Sanchez N. ;Hyslop S. ;Marsh N.A. ;Butterworth P.J.Price R.G.A. Yarleque, S. Campos, E. Escobar, F. Lazo, N. Sanchez, S. Hyslop, N. A. Marsh, P. J. Butterworth and R. G. Price. Isolation and characterization of a fibrinogen-clotting enzyme from venom of the snake Lachesis muta muta(Peruvian bushmaster). Toxicon27, 1189–1197, 1989.—A fibrinogen-clotting enzyme from the venom of the Peruvian bushmaster snake was purified to homogeneity by gel filtration on Sephadex G-100 followed by DEAE-cellulose ion-exchange chromatography using a linear ionic strength gradient with NaCl. -
PublicaciónInter and intra-species-related differences in the regulation of the cardiac autonomic system(Elsevier, 1998)
;León-Velarde F. ;Richalet J.-P. ;Chavez J.-C. ;Kacimi R. ;Rivera-Chira M. ;Palacios J.-A.Clark D.The heart rate response to isoproterenol (HR-Iso), density and affinity (kd) of β-adrenergic (β-AR) and muscarinic (M2) receptors were compared among three rodents with different generation-life histories of confinement and of high altitude exposure. -
PublicaciónStudy of solid-liquid extractions in a batch equipment(Taylor and Francis Ltd., 1998)Escobedo F.A.A batch pilot-scale apparatus is described for the study of processes for obtaining phyto-extracts using solvents. The distinctive feature of the equipment is that it provides the efficiency of a multi-stage counter-current extraction, yet uses only a single batch extractor (as opposed to a battery of extractors). This is achieved by using an auxiliary tank in which intermediate extracts are saved and recirculated in a pre-established order. Careful design of the mechanisms for the circulation of liquid from such tanks has resulted in an apparatus that is compact and has simple, flexible operation. A prototype of this apparatus was constructed for the study of the direct extraction of oil from sunflower seeds using hexane A simple model that describes the operation of the equipment is presented and applied to our experimental work with oilseeds.
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PublicaciónIntestinal parasites of the grey fox (Pseudalopex culpaeus) in the central Peruvian Andes(National Library of Medicine, 1998)
;Moro P.L. ;Ballarta J. ;Gilman R.H. ;Leguia G. ;Rojas M.Montes G.The intestines of 20 grey Peruvian foxes (Pseudalopex culpaeus) were examined for the presence of Echinococcus granulosus and other intestinal parasites. Echinococcus granulosus was not found in foxes but Taenia hydatigena and T. multiceps were found in 7 and 4 animals respectively. The grey fox may not be a suitable definitive host for E. granulosus. However, it may act as a sylvatic reservoir of T. hydatigena and T. multiceps in the central Peruvian Andes. -
PublicaciónHuman hydatidosis in the central Andes of Peru: Evolution of the disease over 3 years(University of Chicago Press, 1999)
;Moro P.L. ;Gilman R.H. ;Verastegui M. ;Bern C. ;Silva B.Bonilla J.J.To document the natural history of Echinococcus granulosus infection and response to treatment of human hydatidosis, we reexamined 28 of 37 subjects with E. granulosus infection diagnosed in an epidemiological study conducted in 1994. Twenty-six (70%) of those 37 subjects underwent abdominal ultrasonography, chest radiography, and enzyme-linked immunoelectrotransfer blot assay in 1997. -
PublicaciónEtiology of acute pneumonia syndrome in beef cattle in Lima [Etiología del síndrome neumónico agudo en vacunos de engorde en Lima](Universidad Nacional Mayor de San Marcos, 2000)
;Zanabria V. ;Rivera H.G.Rosadio R.A.Clinical-, serological and pathological examinations were conducted on twenty feedlot cattle with acute pneumonia from the Department ofLima, in order to determine the etiology ofthe disease. Prior to sacrifice ali the animals were monitored for clinical signs and sera samples taken for serological testing. At postmortem, ali affected lungs were examined grossly and pathological samples were taken to identify viral agents by direct immunoflourescence and/or bacteriological isolation, as well as for histopathological studies. -
PublicaciónSoil microbial community and bacterial functional diversity at Machu Picchu, King George Island, Antarctica(Springer Nature, 2001)
;Lahav Lavian I. ;Vishnevetsky S. ;Barness G.Steinberger Y.The objective of this study was to evaluate the potential contribution of the soil microbial community in the vicinity of two plant covers, Sanionia uncinata and Deschampsia antarctica, at Machu Picchu Station, King George Island, Antarctica. -
PublicaciónEffect of microstructure on the abrasive wear properties of infiltrated tungsten alloys(Elsevier, 2002)Caceres P.G.Tungsten-based metal matrix composites (MMCs) were produced by compacting tungsten powder followed by infiltration with liquid 56Cu–43Zn–1Sn and 60Cu–40Ag. It was found that higher tungsten contents were associated with improved wear resistance. This effect, however, is small compared to the effect of different infiltrant alloys.
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PublicaciónOptimization Criteria in Mössbauer Spectroscopy(Springer Nature, 2003)
;Bravo J.A. ;Cerón M.L.Fabián J.The application of optimization criteria both in sample preparation and instrument configuration is very important in Mössbauer spectroscopy in order to compensate for the long periods of time required for the accumulation of spectra with an adequate statistical resolution. The criterion of optimum sample thickness is rather well known in the Mössbauer community. In this work we emphasize the criteria for optimum saturation level due to dead time and optimum window configuration in the gamma detection system. -
PublicaciónPoaceae from Yanachaga-Chemillén National Park (Oxapampa, Pasco, Perú). Part I: Bambusoideae [Las Poáceas del Parque Nacional Yanachaga-Chemillén, Oxapampa, Pasco, Perú. Parte I: Bambusoideae](Facultad de Ciencias Biologicas, Universidad Nacional Mayor de San Marcos, 2003)
;La-Torre M.I. ;Cano A.Tovar O.This work is the first part of biodiversity study of Poaceae family from Yanachaga-Chemillen National Park and surroundings places (10º35´ - 10º10´ S and 75º10´ - 75º45´ W and from 300 to 3800 m). We analysed the material colected for us since 1995 to 1996 and material deposited in the Herbario San Marcos of Museo de Historia Natural and Missouri Botanical Garden. -
PublicaciónGelatin particle indirect agglutination and enzyme-linked immunosorbent assay for diagnosis of strongyloidiasis using Strongyloides venezuelensis antigen(Oxford University Press, 2003)
;Huaman M.C. ;Sato Y. ;Aguilar J.L. ;Terashima A. ;Guerra H. ;Gotuzzo E.Kanbara H.Routine microscopical examination of stool specimens for diagnosis of strongyloidiasis is insensitive and serological methods using Strongyloides stercoralis antigen are at present not available for field studies. We evaluated 2 techniques, enzyme-linked immunosorbent assay (ELISA) and gelatin particle indirect agglutination (GPIA), using an antigen obtained from the rodent parasite, S. venezuelensis. -
PublicaciónNanocrystallization process in Finemet-type alloys followed by in situ 57Fe Mössbauer spectroscopy(Elsevier, 2004)
;Rodríguez V.A.P. ;Regalado J.F. ;Baggio-Saitovitch E.Passamani E.C.High-temperature in situ Mössbauer spectroscopy was used to investigate the nanocrystallization process in Fe73.5Si13.5B9Cu1Nb1X2 (X=Zr, Nb, Mo and V) amorphous alloys. The Mössbauer spectra were taken at temperatures where only the amorphous phase is found in a paramagnetic state, allowing an accurate resolution between the amorphous and crystalline phases presented in the annealed ribbons. -
PublicaciónPoaceae from Yanachaga-Chemillén National Park (Oxapampa, Peru). Part II: Pooideae, Centothecoideae, Arundinoideae, Chloridoideae and Panicoideae [Las Poáceas del Parque Nacional Yanachaga-Chemillén (Oxapampa, Perú). Parte II: Pooideae, Centothecoideae, Arundinoideae, Chloridoideae y Panicoideae](Facultad de Ciencias Biologicas, Universidad Nacional Mayor de San Marcos, 2004)
;La-Torre M.I. ;Cano A.Tovar O.This work is the first part of biodiversity study of Poaceae family from Yanachaga-Chemillen National Park and surroundings places. We analysed the material colected for us since 1995 to 1996 and material deposited in the Herbario San Marcos of Museo de Historia Natural and Missouri Botanical Garden. -
PublicaciónScreening for cystic echinococcosis in an endemic region of Peru using portable ultrasonography and the enzyme-linked immunoelectrotransfer blot (EITB) assay(Springer Nature, 2005)
;Moro P.L. ;Garcia H.H. ;Gonzales A.E. ;Bonilla J.J. ;Verastegui M.GilmanMD R.H.Cystic echinococcosis (CE) caused by the larval form of Echinococcus granulosus is a major public health problem in sheep-raising regions of the World. This study compared portable ultrasound with the enzyme-linked immunoelectrotransfer blot (EITB) assay as screening methods to estimate the prevalence of human CE in a remote village in the Peruvian Andes. -
PublicaciónRisk factors for canine echinococcosis in an endemic area of Peru(Elsevier, 2005)
;Moro P.L. ;Lopera L. ;Bonifacio N. ;Gonzales A. ;Gilman R.H.Moro M.H.An epidemiological study was conducted in a highland rural community in Peru to determine risk factors for canine echinococcosis caused by Echinococcus granulosus. Dogs were diagnosed using a coproantigen enzyme-linked immunosorbent assay (ELISA). Dog owners were interviewed prior to stool collection and asked for attitudes, practices and beliefs likely to be associated with local patterns of E. granulosus transmission. -
PublicaciónSnO2 thin-films prepared by a spray-gel pyrolysis: Influence of sol properties on film morphologies(Elsevier, 2007)
;Luyo C. ;Fábregas I. ;Reyes L. ;Solís J.L. ;Rodríguez J. ;Estrada W.Candal R.J.Nanostructured tin oxide films were prepared by depositing different sols using the so-called spray–gel pyrolysis process. SnO2 suspensions (sols) were obtained from tin (IV) tert-amyloxide (Sn(t-OAm)4) or tin (IV) chloride pentahydrate (SnCl4·5H2O) precursors, and stabilized with ammonia or tetraethylammonium hydroxide (TEA-OH). Xerogels from the different sols were obtained by solvent evaporation under controlled humidity. -
PublicaciónThe northern Humboldt Current System: Brief history, present status and a view towards the future(Elsevier, 2008)
;Chavez F.P. ;Bertrand A. ;Guevara-Carrasco R. ;Soler P.Csirke J.The tropical ocean off the west coast of South America is notable for several reasons. First, it is unusually cool for an ocean that is so close to the equator with sea surface temperatures at 5 S off Peru as cool as 16 C when most other tropical locations are in excess of 25 C. Upwelling of cool waters brings phytoplankton nutrients to the surface, dramatically increasing biological productivity in this low-latitude region of few storms. S -
PublicaciónSequencing the Potato genome: Outline and first results to come from the Elucidation of the sequence of the world's third most important food crop(Springer Nature, 2009)
;Visser R.G.F. ;Bachem C.W.B. ;de Boer J.M. ;Bryan G.J. ;Chakrabati S.K. ;Feingold S. ;Gromadka R. ;van Ham R.C.H.J. ;Huang S. ;Jacobs J.M.E. ;Kuznetsov B. ;de Melo P.E. ;Milbourne D. ;Orjeda G. ;Sagredo B.Tang X.Potato is a member of the Solanaceae, a plant family that includes several other economically important species, such as tomato, eggplant, petunia, tobacco and pepper. The Potato Genome Sequencing Consortium (PGSC) aims to elucidate the complete genome sequence of potato, the third most important food crop in the world. The PGSC is a collaboration between 13 research groups from China, India, Poland, Russia, the Netherlands, Ireland, Argentina, Brazil, Chile, Peru, USA, New Zealand and the UK. The potato genome consists of 12 chromosomes and has a (haploid) length of approximately 840 million base pairs, making it a medium-sized plant genome. -
PublicaciónTitanium Dioxide onto Polyethylene for Water Decontamination(De Gruyter, 2009)
;Ponce, S ;Carpio, E ;Venero, J ;Estrada, W ;Rodriguez, J ;Reche, CCandal, RJTiO2 aqueous suspensions under illumination of UV range (310-400 nm UV-A) have demonstrated a big potential for water decontamination and disinfection for human consume. Separation of TiO2 from the process is not easy. Supporting TiO2 to a proper substrate avoid the separation step after the photocatalytic treatment. This procedure results very interesting for the manufacturing of economic decontamination devices, which could be made with lightweight and flexible materials, bringing much versatility for the design of reactors for water decontamination. Based on those requirements, supporting TiO2 over polyethylene results ideal for that purposes due to its physicochemical properties, good transparency and low cost. In this work we evaluated different methods to support titanium dioxide nanoparticles onto polyethylene. -
PublicaciónEvaluating soil rhizobacteria for their ability to enhance plant growth and tuber yield in potato(Wiley, 2010)
;Oswald, A ;Velez, PC ;Davila, DZPineda, JAThe objectives of this study were to identify promising microorganisms to improve potato productivity in low-input systems of tropical highlands and to compare results from in vitro, greenhouse and field experiments to advance the development of a screening method for rhizobacteria and develop an efficient assessment of their effect on plant growth in field conditions. A total of 150 bacterial strains were screened in vitro, in greenhouse and field trials.