Cholera in Lima, Peru, correlates with prior isolation of Vibrio cholerae from the environment Franco A.A. es_PE Fix A.D. es_PE Prada A. es_PE Paredes E. es_PE Palomino J.C. es_PE Wright A.C. es_PE Johnson J.A. es_PE McCarter R. es_PE Guerra H. es_PE Glenn Morris Jr. J. es_PE 2024-05-30T23:13:38Z 2024-05-30T23:13:38Z 1997
dc.description These studies were supported by grants from the Thrasher Research Fund and the Peruvian National Council for Science and Technology (CONCYTEC).
dc.description.abstract The authors utilized a recently developed DNA probe technique to obtain quantitative data on occurrence of Vibrio cholerae in samples collected monthly from 12 environmental sites in Lima, Peru, from November 1993 through March 1995. Peak V. cholerae counts ranged from 1027/ml to 105/ml, with the highest counts in sewage-contaminated areas and irrigation water. With our methodology, no V. cholerae cases were detected at any site during the winter months of July through October. Counts were detectable in the environment before onset of cholera in the community, with counts at “cleaner” sites upriver correlating significantly with occurrence of community disease 2 and 3 months later. In sites with heavy sewage contamination, V. cholerae could still be detected before the onset of cases in the community; however, in contrast to upriver sites, counts at these latter sites correlated most closely with the number of concurrently occurring cholera cases. These data support a model of cholera seasonality in which initial increases in number of V. cholerae in the environment (possibly triggered by temperature) are followed by onset of illness in the community, with these human cases further amplifying the organism as the epidemic cycle proceeds. Am J Epidemiol 1997;146: 1067–75.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.scopus 2-s2.0-0031474247
dc.language.iso eng
dc.publisher Oxford University Press
dc.relation.ispartof American Journal of Epidemiology
dc.rights info:eu-repo/semantics/openAccess
dc.subject water sampling
dc.subject article es_PE
dc.subject bacterium culture es_PE
dc.subject bacterium isolation es_PE
dc.subject DNA probe es_PE
dc.subject nonhuman es_PE
dc.subject Peru es_PE
dc.subject Vibrio cholerae es_PE
dc.subject waste water es_PE
dc.title Cholera in Lima, Peru, correlates with prior isolation of Vibrio cholerae from the environment
dc.type info:eu-repo/semantics/article
Paquete original
Mostrando 1 - 1 de 1
Imagen en miniatura
1997_Cholera in Lima, Peru, correlates with prior isolation of Vibrio cholerae from the environment.pdf
757.83 KB
Adobe Portable Document Format