Publicación:
Genome-Wide Identification and Mapping of NBS-Encoding Resistance Genes in Solanum tuberosum Group Phureja
Genome-Wide Identification and Mapping of NBS-Encoding Resistance Genes in Solanum tuberosum Group Phureja
| dc.contributor.author | Lozano, R | es_PE |
| dc.contributor.author | Ponce, O | es_PE |
| dc.contributor.author | Ramirez, M | es_PE |
| dc.contributor.author | Mostajo, N | es_PE |
| dc.contributor.author | Orjeda, G | es_PE |
| dc.date.accessioned | 2024-05-30T23:13:38Z | |
| dc.date.available | 2024-05-30T23:13:38Z | |
| dc.date.issued | 2012 | |
| dc.description | (099-FINCyT-EQUIP-2009)/(076-FINCyT-PIN-2008) | |
| dc.description.abstract | The majority of disease resistance (R) genes identified to date in plants encode a nucleotide-binding site (NBS) and leucine-rich repeat (LRR) domain containing protein. Additional domains such as coiled-coil (CC) and TOLL/interleukin-1 receptor (TIR) domains can also be present. In the recently sequenced Solanum tuberosum group phureja genome we used HMM models and manual curation to annotate 435 NBS-encoding R gene homologs and 142 NBS-derived genes that lack the NBS domain. Highly similar homologs for most previously documented Solanaceae R genes were identified. A surprising ∼41% (179) of the 435 NBS-encoding genes are pseudogenes primarily caused by premature stop codons or frameshift mutations. Alignment of 81.80% of the 577 homologs to S. tuberosum group phureja pseudomolecules revealed non-random distribution of the R-genes; 362 of 470 genes were found in high density clusters on 11 chromosomes. | |
| dc.description.sponsorship | Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec | |
| dc.identifier.doi | https://doi.org/10.1371/journal.pone.0034775 | |
| dc.identifier.isi | 305012700058 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12390/1249 | |
| dc.language.iso | eng | |
| dc.publisher | PLOS | |
| dc.relation.ispartof | PLOS ONE | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Protein domains | |
| dc.subject | Plant genomics | es_PE |
| dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#4.00.00 | |
| dc.title | Genome-Wide Identification and Mapping of NBS-Encoding Resistance Genes in Solanum tuberosum Group Phureja | |
| dc.type | info:eu-repo/semantics/article | |
| dspace.entity.type | Publication |