Publicación:
PDMS lab-on-a-chip fabrication using 3D printed templates

dc.contributor.author Comina, G es_PE
dc.contributor.author Suska, A es_PE
dc.contributor.author Filippini, D es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2014
dc.description G. Comina's research stay at Linkoping University has been financed by the Peruvian National Council for Science and Technology (CONCYTEC). This research has been supported by grants from Linkoping Centre for Life Science Technologies (LIST), Sweden, and from the Swedish Research Council (VR).
dc.description.abstract The fabrication of conventional PDMS on glass lab-on-a-chip (LOC) devices, using templates printed with a commercial (2299 US$) micro-stereo lithography 3D printer, is demonstrated. Printed templates replace clean room and photolithographic fabrication resources and deliver resolutions of 50 μm, and up to 10 μm in localized hindrances, whereas the templates are smooth enough to allow direct transfer and proper sealing to glass substrates. 3D printed templates accommodate multiple thicknesses, from 50 μm up to several mm within the same template, with no additional processing cost or effort. This capability is exploited to integrate silicone tubing easily, to improve micromixer performance and to produce multilevel fluidics with simple access to independent functional surfaces, which is illustrated by time-resolved glucose detection. The templates are reusable, can be fabricated in under 20 min, with an average cost of 0.48 US$, which promotes broader access to established LOC configurations with minimal fabrication requirements, relieves LOC fabrication from design skills and provides a versatile LOC development platform.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.1039/c3lc50956g
dc.identifier.isi 328910700019
dc.identifier.uri https://hdl.handle.net/20.500.12390/1116
dc.language.iso eng
dc.publisher Royal Society of Chemistry
dc.relation.ispartof Lab on a Chip
dc.rights info:eu-repo/semantics/openAccess
dc.subject Stereolithography
dc.subject 3D Printers es_PE
dc.subject Fabrication es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#2.05.01
dc.title PDMS lab-on-a-chip fabrication using 3D printed templates
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
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