Publicación:
Chromosomal Localization of Candidate Genes for Fiber Growth and Color in Alpaca (Vicugna pacos)

Página de artículo simple
dc.contributor.author Mendoza, MN es_PE
dc.contributor.author Raudsepp, T es_PE
dc.contributor.author Alshanbari, F es_PE
dc.contributor.author Gutierrez, G es_PE
dc.contributor.author de Leon, FAP es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2019
dc.description.abstract The alpaca (Vicugna pacos) is an economically important and cultural signature species in Peru. Thus, molecular genomic information about the genes underlying the traits of interest, such as fiber properties and color, is critical for improved breeding and management schemes. Current knowledge about the alpaca genome, particularly the chromosomal location of such genes of interest is limited and lags far behind other livestock species. The main objective of this work was to localize alpaca candidate genes for fiber growth and color using fluorescence in situ hybridization (FISH). We report the mapping of candidate genes for fiber growth COL1A1, CTNNB1, DAB2IP, KRT15, KRTAP13-1, and TNFSF12 to chromosomes 16, 17, 4, 16, 1, and 16, respectively. Likewise, we report the mapping of candidate genes for fiber color ALX3, NCOA6, SOX9, ZIC1, and ZIC5 to chromosomes 9, 19, 16, 1, and 14, respectively. In addition, since KRT15 clusters with five other keratin genes (KRT31, KRT13, KRT9, KRT14, and KRT16) in scaffold 450 (Vic.Pac 2.0.2), the entire gene cluster was assigned to chromosome 16. Similarly, mapping NCOA6 to chromosome 19, anchored scaffold 34 with 8 genes, viz., RALY, EIF2S2, XPOTP1, ASIP, AHCY, ITCH, PIGU, and GGT7 to chromosome 19. These results are concordant with known conserved synteny blocks between camelids and humans, cattle and pigs.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.3389/fgene.2019.00583
dc.identifier.isi 472059700001
dc.identifier.uri https://hdl.handle.net/20.500.12390/1040
dc.language.iso eng
dc.publisher Frontiers in Genetics
dc.relation.ispartof Frontiers in Genetics
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject Peces
dc.subject Alpaca es_PE
dc.subject Cromosomas es_PE
dc.subject Mapeo es_PE
dc.subject Fibra es_PE
dc.subject Genes es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.11
dc.title Chromosomal Localization of Candidate Genes for Fiber Growth and Color in Alpaca (Vicugna pacos)
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
Archivos
Colecciones
1.1 Eventos institucionales
 6.1 Proyectos de investigación científica