HP and EBVaGC in Peruvian patients Lopez, CB es_PE Garcia, MC es_PE Altamirano, CAC es_PE Bolanos, LFB es_PE Leonardo, D es_PE Meza, EP es_PE Bernaola, VV es_PE Prado, JN es_PE Sifuentes, JRS es_PE Monsalve, LAB es_PE Sanchez, MACLR es_PE Dionisio, OM es_PE Passiuri, IC es_PE 2024-05-30T23:13:38Z 2024-05-30T23:13:38Z 2018
dc.description.abstract Gastric cancer (GC) is the second most common cancer and first leading cause of cancer-related deaths in Peru. Infection by Helicobacter pylori (HP) and Epstein-Barr virus (EBV) are accepted carcinogenic and infection is widely spread in the Peruvian population. The aims of this study were to evaluate HP and EBV-associated GC (EBVaCG), to assess the prevalence rate and to define the characteristics of Peruvian patients. GC samples were prospectively collected from patients who underwent gastroscopy or surgical resection with no preoperative treatment at INEN between 2015 and 2017. Tumor tissue (T), proximal healthy tissue (P) and distal healthy tissue (D) samples were assessed for HP and EBV by quantitative PCR (qPCR) using specific primers. HP and EBV status were analyzed along with clinicopathologic parameters of the tumor. Kaplan-Meier estimation curves overall survival (OS) was applied. Comparison between qPCR detection and current standard methods of detection was also performed. All tests were two sided, and a p≤0.05 was considered statistically significant.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.isi 468819502407
dc.language.iso eng
dc.publisher American Association for Cancer Research
dc.rights info:eu-repo/semantics/openAccess
dc.subject Helicobacter pylori
dc.subject Gastric cancer es_PE
dc.subject Epstein-Barr virus es_PE
dc.title HP and EBVaGC in Peruvian patients
dc.type info:eu-repo/semantics/conferenceObject
dspace.entity.type Publication