Publicación:
A computer algorithm for detection of tuberculosis bacilli in Ziehl Nellsen sputum smear images based on the adjustment of RGB primary component tones and geometric eccentricity

dc.contributor.author Del Carpio C. es_PE
dc.contributor.author Dianderas E. es_PE
dc.contributor.author Zimick M. es_PE
dc.contributor.author Sheen P. es_PE
dc.contributor.author Coronel J. es_PE
dc.contributor.author Fuentes P. es_PE
dc.contributor.author Kemper G. es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2017
dc.description.abstract The present study proposes a method of automatic detection of tuberculosis (TB) bacilli from digital images of Ziehl Neelsen sputum smear baciloscopy. The method is based on an algorithm that aims to automate the interpretation of optical microscopic images of sputum smears. According to the World Health Organization (WHO), a specialist can not analyze and process more than 20 samples per day (in order to not affect the analysis sensitivity and commit errors in diagnosis). Therefore, an automated tool as the proposed here, is an important contribution to the current efforts to fight tuberculosis. The algorithm is based on geometric eccentricity of ellipses and improvement of RGB component tones. Correspondence functions adjusted to sample preparation conditions were applied in order to improve the RGB primary component tones of the image. This allows to obtain an adequate segmentation of interest objects. For the recognition of each object as bacillus, the geometric descriptor of eccentricity of the ellipse was applied. The algorithm was validated with 66 independent sputum samples from TB patients. A sensitivity of 88.75% and a specificity of 95.5% was obtained for the diluted pellet method for sample preparation. © by the International Institute of Informatics and Systemics. en
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.isbn urn:isbn:9781941763599
dc.identifier.scopus 2-s2.0-85032367882
dc.identifier.uri https://hdl.handle.net/20.500.12390/484
dc.language.iso eng
dc.publisher International Institute of Informatics and Systemics, IIIS
dc.relation.ispartof WMSCI 2017 - 21st World Multi-Conference on Systemics, Cybernetics and Informatics, Proceedings
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject Ziehl-neelsen
dc.subject Algorithms es_PE
dc.subject Bacilli es_PE
dc.subject Bacteriology es_PE
dc.subject Cybernetics es_PE
dc.subject Cybernetics es_PE
dc.subject Diagnosis es_PE
dc.subject Geometry es_PE
dc.subject Image enhancement es_PE
dc.subject Image enhancement es_PE
dc.subject Image processing es_PE
dc.subject Optical data processing es_PE
dc.subject Plasma diagnostics es_PE
dc.subject Sensitivity analysis es_PE
dc.subject Baciloscopy es_PE
dc.subject Digital image es_PE
dc.subject Sputum smear es_PE
dc.title A computer algorithm for detection of tuberculosis bacilli in Ziehl Nellsen sputum smear images based on the adjustment of RGB primary component tones and geometric eccentricity
dc.type info:eu-repo/semantics/conferenceObject
dspace.entity.type Publication
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