5.1 Proyectos de Innovación y transferencia tecnológica
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PublicaciónIsolation and characterization of a fibrinogen-clotting enzyme from venom of the snake, Lachesis muta muta(Peruvian bushmaster)(Elsevier, 1989)A. Yarleque, S. Campos, E. Escobar, F. Lazo, N. Sanchez, S. Hyslop, N. A. Marsh, P. J. Butterworth and R. G. Price. Isolation and characterization of a fibrinogen-clotting enzyme from venom of the snake Lachesis muta muta(Peruvian bushmaster). Toxicon27, 1189–1197, 1989.—A fibrinogen-clotting enzyme from the venom of the Peruvian bushmaster snake was purified to homogeneity by gel filtration on Sephadex G-100 followed by DEAE-cellulose ion-exchange chromatography using a linear ionic strength gradient with NaCl.
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PublicaciónAutomatic detection of pneumonia analyzing ultrasound digital images(IEEE, 2016)Pneumonia is one of the major causes of child mortality. Unfortunately, in developing countries there is a lack of infrastructure and medical experts in rural areas to provide the required diagnostics opportunely. Lung ultrasound echography has proved to be an important tool to detect lung consolidates as evidence of pneumonia.
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PublicaciónAnalysis of Hydrodynamic Patterns and Suspended Sediment Transport in the Virrilá Estuary-Peru(American Society of Civil Engineers (ASCE), 2018)As of today the Virrilá Estuary located in Piura, Peru, is polluted with high nitrate and chlorine concentrations. Because of that the mariculture activity of the towns and cities located in that estuary are significantly affected (which is the basis of their economy). Recent field measurements indicate that the nitrate concentrations are related to the suspended sediment concentrations whereas the chlorine distribution is directly associated with the flow recirculation patterns. In order to shed light on the transport dynamics of these contaminants a two-dimensional shallow water equations numerical model that can predict suspended sediment transport and flow recirculation was developed.
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PublicaciónEmpirical–statistical downscaling of austral summer precipitation over south america, with a focus on the central peruvian andes and the equatorial amazon basin(American Meteorological Society, 2020)Precipitation is one of the most difficult variables to estimate using large-scale predictors. Over South America (SA), this task is even more challenging, given the complex topography of the Andes. Empirical–statistical downscaling (ESD) models can be used for this purpose, but such models, applicable for all of SA, have not yet been developed. To address this issue, we construct an ESD model using multiple-linear-regression techniques for the period 1982–2016 that is based on large-scale circulation indices representing tropical Pacific Ocean, Atlantic Ocean, and South American climate variability, to estimate austral summer [December–February (DJF)] precipitation over SA. Statistical analyses show that the ESD model can reproduce observed precipitation anomalies over the tropical Andes (Ecuador, Colombia, Peru, and Bolivia), the eastern equatorial Amazon basin, and the central part of the western Argentinian Andes. On a smaller scale, the ESD model also shows good results over the Western Cordillera of the Peruvian Andes. The ESD model reproduces anomalously dry conditions over the eastern equatorial Amazon and the wet conditions over southeastern South America (SESA) during the three extreme El Niños: 1982/83, 1997/98, and 2015/16. However, it overestimates the observed intensities over SESA. For the central Peruvian Andes as a case study, results further show that the ESD model can correctly reproduce DJF precipitation anomalies over the entire Mantaro basin during the three extreme El Niño episodes. Moreover, multiple experiments with varying predictor combinations of the ESD model cor-roborate the hypothesis that the interaction between the South Atlantic convergence zone and the equatorial Atlantic Ocean provoked the Amazon drought in 2015/16. © 2021 American Meteorological Society.
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Publicación3D-printed hand orthotics for the management of spasticity in cerebral palsy(Springer Nature, 2018-02-02)Cerebral palsy is a highly debilitating disorder that results from brain damage during development or birth. It can cause motor and language disabilities. Spasticity is one common complication of cerebral palsy which makes movement of upper and lower limbs difficult and often causes joint deformities. To manage spasticity, less intrusive recommendations include the use of hand orthotics. However, in resource-constrained areas, orthotics are often unaffordable and poorly constructed. 3D-printed orthotics could provide an innovative solution, as they utilize high precision manufacturing with low-cost materials. The aim of this study is to determine whether 3D printed orthotics are as effective as conventional orthotics at preventing hand deformities in children with cerebral palsy.
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