Publicación:
Breast elastography: Identification of benign and malignant cancer based on absolute elastic modulus measurement using vibro-elastography

dc.contributor.author Arroyo J. es_PE
dc.contributor.author Saavedra A.C. es_PE
dc.contributor.author Guerrero J. es_PE
dc.contributor.author Montenegro P. es_PE
dc.contributor.author Aguilar J. es_PE
dc.contributor.author Pinto J.A. es_PE
dc.contributor.author Lobo J. es_PE
dc.contributor.author Salcudean T. es_PE
dc.contributor.author Lavarello R. es_PE
dc.contributor.author Castañeda B. es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2018
dc.description.abstract Breast cancer is a public health problem with ? 1.7 million new cases per year worldwide and with several limitations in the state-of-art screening techniques. Ultrasound elastography involves a set of techniques intended to facilitate the noninvasive diagnosis of cancer. Among these, Vibro-elastography is an ultrasound-based technique that employs external mechanical excitation to infer the elastic properties of soft tissue. In this paper, we evaluate the Vibro-elastography performance in the differentiation of benign and malignant breast lesions. For this study, a group of 18 women with clinically confirmed tumors or suspected malignant breast lesions were invited to participate. For each volunteer, an elastogram was obtained, and the mean elasticity of the lesion and the adjacent healthy tissue were calculated. After the acquisition, the volunteers underwent core-needle biopsy. The histopathological results allowed to validate the Vibro-elastography diagnosis, which ranged from benign to malignant lesions. Results indicate that the mean elasticity value of the benign lesions, malignant lesions and healthy breast tissue were 39.4 ± 12 KPa, 55.4 ± 7.02 KPa and 23.91 ± 4.57 kPa, respectively. The classification between benign and malignant breast cancer was performed using Support Vector Machine based on the measured lesion stiffness. A ROC curve permitted to quantify the accuracy of the differentiation and to define a suitable cutoff value of stiffness, obtaining an AUC of 0.90 and a cutoff value of 44.75 KPa. The results obtained suggest that Vibro-elastography allows differentiating between benign and malignant lesions. Furthermore, the elasticity values obtained for benign, malignant and healthy tissue are consistent with previous reports. © 2018 SPIE.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.1117/12.2293664
dc.identifier.scopus 2-s2.0-85047880305
dc.identifier.uri https://hdl.handle.net/20.500.12390/2778
dc.language.iso eng
dc.publisher SPIE
dc.relation.ispartof Progress in Biomedical Optics and Imaging - Proceedings of SPIE
dc.rights info:eu-repo/semantics/openAccess
dc.subject Vibro-elastography
dc.subject breast cancer es_PE
dc.subject elastography es_PE
dc.subject.ocde http://purl.org/pe-repo/ocde/ford#3.02.28
dc.title Breast elastography: Identification of benign and malignant cancer based on absolute elastic modulus measurement using vibro-elastography
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
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