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Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon

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dc.contributor.author Vargas-arana G. es_PE
dc.contributor.author Merino-zegarra C. es_PE
dc.contributor.author Riquelme-penaherrera M. es_PE
dc.contributor.author Nonato-ramirez L. es_PE
dc.contributor.author Delgado-wong H. es_PE
dc.contributor.author Pertino M.W. es_PE
dc.contributor.author Parra C. es_PE
dc.contributor.author Simirgiotis M.J.J. es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2021
dc.description Funding: This research was funded by the Project Concytec – Banco Mundial “Mejoramiento y Ampliación de los Servicios del Sistema Nacional de Ciencia Tecnología e Innovación Tecnológica” 8682, through its executing unit Fondecyt [Contrato N° 119-2018-FONDECYT-BM-IADT-MU]. M. J. S acknowledge fondecyt 1180059.
dc.description.abstract Cocona fruits are a popular food and medicinal fruit used mainly in the Amazon and several countries of South America for the preparation of several food products such as drinks, jams and milk shakes. In this study five ecotypes of cocona native to Peru have been studied regarding their nutritional and antioxidants values plus antihyperlipidemic activities. Seventy bioactive compounds have been detected in Peruvian cocona ecotypes including several phenolic acids, aminoacids and flavonoids; of those six were spermidines, (peaks 1, 2, 25, 26, 38 and 39), thirteen were aminoacids, (peaks 3,-9, 11-13, 16, 17, 22-24), eighteen flavonoids (peaks 28, 30-32 45,46, 48-53 56, 57, 61 and 64-66), twelve were phenolics (peaks 19, 21, 27, 29, 34, 35, 36, 42, 43, 44, 54, and 59), two carotenoids, (peak 62 and 63), eight were lipid derivatives (peaks 37, 55, 58, 60 and 67-70), one sugar (peak 47), four terpenes (peaks 33, 40, 41 and 47), two amides, (peaks 10 and 18), one aldehyde, (peak 15), and three saturated organic acids, (peaks 4, 5 and 20). Hypercholesterolemic rats administered with pulp of the ecotypes CTR and SRN9 showed the lowest cholesterol and triglyceride levels after treatment (126.74 ± 6.63; 102.11 ± 9.47; 58.16 ± 6.64; 61.05 ± 4.00 mg/dL, for cholesterol, triglycerides, high-density lipoprotein and low-density lipoprotein respectively, for the group treated with SRN9 pulp, and 130.09 ± 8.55; 108.51 ± 10.04; 57.30 ± 5.72; and 65.41 ± 7.68 mg/dL, for cholesterol, triglycerides, HDL and LDL lipoproteins respectively for the group treated with CTR pulp). The ecotypes proved to be good sources of natural antioxidants and their consumption represent an alternative for the prevention of atherosclerosis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.3390/antiox10101566
dc.identifier.scopus 2-s2.0-85116075201
dc.identifier.uri https://hdl.handle.net/20.500.12390/2970
dc.language.iso eng
dc.publisher MDPI
dc.relation.ispartof Antioxidants
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject UHPLC-PDA-ESI-OT-MS
dc.subject Antihyperlipidemic es_PE
dc.subject Antioxidant activity es_PE
dc.subject Nutritional values es_PE
dc.subject Phenolics es_PE
dc.subject Solanaceae es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.04
dc.title Antihyperlipidemic and antioxidant capacities, nutritional analysis and uhplc-pda-ms characterization of cocona fruits (Solanum sessiliflorum dunal) from the peruvian amazon
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
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