Oropouche infection a neglected arbovirus in patients with acute febrile illness from the Peruvian coast

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Martins-Luna J.
Del Valle-Mendoza J.
Silva-Caso W.
Sandoval I.
Del Valle L.J.
Palomares-Reyes C.
Carrillo-Ng H.
Peña-Tuesta I.
Aguilar-Luis M.A.
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BioMed Central Ltd.
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Objective: To evaluate the frequency of infection caused by the Oropouche virus (OROV) in 496 patients with acute febrile disease (AFI), whose samples were obtained for the analysis of endemic arboviruses in a previous investigation carried out in 2016. Results: OROV was detected in 26.4% (131/496) of serum samples from patients with AFI. Co-infections with Dengue virus (7.3%), Zika virus (1.8%) and Chikungunya (0.2%) were observed. The most common clinical symptoms reported among the patients with OROV infections were headache 85.5% (112/131), myalgia 80.9% (106/131), arthralgia 72.5% (95/131) and loss of appetite 67.9% (89/131). Headache and myalgia were predominant in all age groups. Both OROV infections and co-infections were more frequent in May, June and July corresponding to the dry season of the region. © 2020 The Author(s).
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Zika, Arbovirus, Chikungunya, Dengue, Oropouche, PCR, Peru