Loop-mediated isothermal DNA amplification for asymptomatic malaria detection in challenging field settings: Technical performance and pilot implementation in the Peruvian Amazon

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Aguilar L.A.
Coveñas R.
Díaz-Cabiale Z.
Mangas A.
Medina L.E.
Narváez J.A.
Sánchez M.L.
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Public Library of Science
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Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of implementing this technique for population screenings in isolated field settings.
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protozoal DNA, adolescent, adult, Amazon, Article, asymptomatic disease, bright field microscopy, child, controlled clinical trial, controlled study, cross-sectional study, density, diagnostic accuracy, diagnostic kit, diagnostic test accuracy study, diagnostic value, disease carrier, DNA determination, feasibility study, female, field study, gene amplification, human, intermethod comparison, loop mediated isothermal amplification, major clinical study, malaria, malaria falciparum, male, mass screening, mixed infection, molecular diagnosis, parasite density, parasite identification, Peru