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Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections
Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections
| dc.contributor.author | Abascal E. | es_PE |
| dc.contributor.author | Herranz M. | es_PE |
| dc.contributor.author | Acosta F. | es_PE |
| dc.contributor.author | Agapito J. | es_PE |
| dc.contributor.author | Cabibbe A.M. | es_PE |
| dc.contributor.author | Monteserin J. | es_PE |
| dc.contributor.author | Ruiz Serrano M.J. | es_PE |
| dc.contributor.author | Gijón P. | es_PE |
| dc.contributor.author | Fernández-González F. | es_PE |
| dc.contributor.author | Lozano N. | es_PE |
| dc.contributor.author | Chiner-Oms Á. | es_PE |
| dc.contributor.author | Cáceres T. | es_PE |
| dc.contributor.author | Pintado P.G. | es_PE |
| dc.contributor.author | Acín E. | es_PE |
| dc.contributor.author | Valencia E. | es_PE |
| dc.contributor.author | Muñoz P. | es_PE |
| dc.contributor.author | Comas I. | es_PE |
| dc.contributor.author | Cirillo D.M. | es_PE |
| dc.contributor.author | Ritacco V. | es_PE |
| dc.contributor.author | Gotuzzo E. | es_PE |
| dc.contributor.author | García de Viedma D. | es_PE |
| dc.date.accessioned | 2024-05-30T23:13:38Z | |
| dc.date.available | 2024-05-30T23:13:38Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | It is relevant to evaluate MDR-tuberculosis in prisons and its impact on the global epidemiology of this disease. However, systematic molecular epidemiology programs in prisons are lacking. A health-screening program performed on arrival for inmates transferred from Peruvian prisons to Spain led to the diagnosis of five MDR-TB cases from one of the biggest prisons in Latin America. They grouped into two MIRU-VNTR–clusters (Callao-1 and Callao-2), suggesting a reservoir of two prevalent MDR strains. A high-rate of overexposure was deduced because one of the five cases was coinfected by a pansusceptible strain. Callao-1 strain was also identified in 2018 in a community case in Spain who had been in the same Peruvian prison in 2002–5. A strain-specific-PCR tailored from WGS data was implemented in Peru, allowing the confirmation that these strains were currently responsible for the majority of the MDR cases in that prison, including a new mixed infection. © 2020, The Author(s). | |
| dc.description.sponsorship | Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec | |
| dc.identifier.citation | Abascal, E., Herranz, M., Acosta, F. et al. Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections. Sci Rep 10, 2704 (2020). https://doi.org/10.1038/s41598-020-59373-w | |
| dc.identifier.doi | https://doi.org/10.1038/s41598-020-59373-w | |
| dc.identifier.scopus | 2-s2.0-85079612900 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12390/2447 | |
| dc.language.iso | eng | |
| dc.publisher | Nature Research | |
| dc.relation.ispartof | Scientific Reports | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Humans | |
| dc.subject | Antitubercular Agents | es_PE |
| dc.subject | Bacterial Typing Techniques | es_PE |
| dc.subject | Coinfection | es_PE |
| dc.subject | Drug Resistance | es_PE |
| dc.subject.ocde | http://purl.org/pe-repo/ocde/ford#3.03.08 | |
| dc.title | Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections | |
| dc.type | info:eu-repo/semantics/article | |
| dspace.entity.type | Publication |
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