Publicación:
Bioactive membranes of polymeric micro and nanocomposites prepared with the natural anionic marine polysaccharide (Alginate) functionalized with extracts of cat’s claw (uncaria tomentosa) and aloe vera

dc.contributor.author Kim S. es_PE
dc.contributor.author Elgegren M. es_PE
dc.contributor.author Donayre A. es_PE
dc.contributor.author Galaretta B. es_PE
dc.contributor.author Nakamatsu J. es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2020
dc.description.abstract In this research, the nanostructured alginate (AL) membranes were prepared with natural bioactive compound, Cat's claw (Uncaria tomentosa) extract (UT). UT is broadly used as an anti-inflammatory agent and the effect on the treatment of Rheumatism was proved by many scientists. For this reason, we added this bioactive compound in the process of AL membrane formulation to improve the biological activities. 2-dimentional (2-D) and 3-dimentional (3-D) AL membranes were prepared with and without addition of UT extracts. 3-D AL membranes were prepared using ultrasound with high intensity. The wettability of AL membranes depending on the concentration of AL was studied by measuring contact angle and surface energy. Stabilization agent, poloxamer 407, was used to improve the stability of AL nanoemulsion. The effects of UT in 3-D AL membranes were studied by measuring swelling behavior and contact angle. The surface morphology was measured with scanning electron microscopy (SEM). Comparing to 2-D AL membranes, 3-D AL membranes presented rougher surface due to AL nanoparticles presence. When UT was incorporated in AL membranes, strong antioxidant activity and higher contact angle and swelling ratio were observed than non-UT incorporated AL membranes. © 2020 Trans Tech Publications Ltd, Switzerland.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.4028/www.scientific.net/MSF.1007.131
dc.identifier.scopus 2-s2.0-85090350389
dc.identifier.uri https://hdl.handle.net/20.500.12390/2643
dc.language.iso eng
dc.publisher Trans Tech Publications Ltd
dc.relation.ispartof Materials Science Forum
dc.rights info:eu-repo/semantics/openAccess
dc.subject Uncaria tomentose
dc.subject Alginate es_PE
dc.subject Anti-inflammatory activity es_PE
dc.subject Antioxidant activity es_PE
dc.subject Biodegradable es_PE
dc.subject.ocde http://purl.org/pe-repo/ocde/ford#2.02.01
dc.title Bioactive membranes of polymeric micro and nanocomposites prepared with the natural anionic marine polysaccharide (Alginate) functionalized with extracts of cat’s claw (uncaria tomentosa) and aloe vera
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
Archivos