Publicación:
In vivo estimation of the Young's modulus in normal human dermis

dc.contributor.author Saavedra A.C. es_PE
dc.contributor.author Arroyo J. es_PE
dc.contributor.author Zvietcovich F. es_PE
dc.contributor.author Lavarello R.J. es_PE
dc.contributor.author Castaneda B. es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2018
dc.description.abstract Skin elastic properties change during a cutaneous disorder or in the aging process. Deep knowledge of skin layers helps monitoring and diagnosing structural changes. High frequency ultrasound (HF-US) has been recently introduced to diagnose and evaluate some dermatological disorders in the clinical practice. US elastography adds elasticity information of the analyzed tissue. In particular, harmonic elastography estimates the speed of shear waves produced by external vibration sources, in order to relate the shear wave speed to the Young's modulus. In the epidermis and dermis layers, shear waves are not generated; in contrast, surface acoustic waves (SAWs) exist as they propagate in the top of the tissue. This study uses crawling wave sonoelastography for the estimation of SAWs in human thigh dermis in vivo. Experiments were performed in ten volunteers in the range of 200 - 500 Hz. As other studies suggest, SAW speed needs to be compensated to reach shear wave speed, for calculating the Young's modulus. Thus, the SAW speed estimated was corrected when it propagates in solidUS gel interface. Specifically, the elasticity modulus found was 18.35 ± 1.04 KPa for a vibration frequency of 200 Hz. Results suggest that the elasticity modulus can be estimated in vivo using crawling wave HF-US for skin application and shows potential for future application in skin disorders. © 2018 IEEE.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.1109/EMBC.2018.8512935
dc.identifier.scopus 2-s2.0-85056618843
dc.identifier.uri https://hdl.handle.net/20.500.12390/2764
dc.language.iso eng
dc.publisher Institute of Electrical and Electronics Engineers Inc.
dc.relation.ispartof Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
dc.rights info:eu-repo/semantics/openAccess
dc.subject surface acoustic waves
dc.subject crawling wave sonoelastography es_PE
dc.subject elastography es_PE
dc.subject High-frequency ultrasound es_PE
dc.subject shear waves es_PE
dc.subject.ocde http://purl.org/pe-repo/ocde/ford#3.02.15
dc.title In vivo estimation of the Young's modulus in normal human dermis
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
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