Publicación:
Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung

dc.contributor.author Caucha L.J. es_PE
dc.contributor.author Frei S. es_PE
dc.contributor.author Rubio O. es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2018
dc.description We gratefully acknowledge financial support by CONCYTEC Peru within the program Programa nacional de innovación para la competitividad y productividad (PNICP, 361-PNICP-PIBA-2014) as well as travel support by the Heidelberg Graduate School of Mathematical and Computational Methods for the Sciences (HGS MathComp). The second author was supported by the DFG Research Scholarship FR3935/1-1.
dc.description.abstract In this article, we present a numerical framework based on continuum models for the fluid dynamics and the CO2 gas distribution in the alveolar sacs of the human lung during expiration and inspiration, including the gas exchange to the cardiovascular system. We include the expansion and contraction of the geometry by means of the Arbitrary Lagrangian–Eulerian (ALE) method. For discretisation, we use equal-order finite elements in combination with pressure-stabilisation techniques based on local projections or interior penalties. We derive formulations for both techniques that are suitable on arbitrarily anisotropic meshes. These formulations are novel within the ALE method. Moreover, we investigate the effect of different boundary conditions, that vary between inspiration and expiration. We present numerical results on a simplified two-dimensional alveolar sac geometry and investigate the influence of the pressure stabilisations as well as the boundary conditions.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.1007/s40314-018-0692-5
dc.identifier.scopus 2-s2.0-85058165129
dc.identifier.uri https://hdl.handle.net/20.500.12390/852
dc.language.iso eng
dc.publisher Springer Science and Business Media, LLC
dc.relation.ispartof Computational and Applied Mathematics
dc.rights info:eu-repo/semantics/openAccess
dc.subject Método arbitrario Lagrangiano-Euleriano (ALE)
dc.subject Dinámica de gases alveolares es_PE
dc.subject Estabilización de presión anisotrópica es_PE
dc.subject Condiciones de contorno artificiales es_PE
dc.subject Estabilización de proyección local es_PE
dc.subject Estabilización de penalti interior es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.02.01
dc.title Finite element simulation of fluid dynamics and CO 2 gas exchange in the alveolar sacs of the human lung
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
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