Bienvenido al Repositorio Institucional del Concytec

El Repositorio Institucional del Concytec tiene como objetivo permitir el libre acceso a la producción científica institucional, optimizando su visibilidad; así mismo garantizar la preservación y conservación de la información relacionada a la ciencia, tecnología e innovación.



Display.item.jsp


Por favor, utiliza este identificador para citar o enlazar este ítem:
http://hdl.handle.net/20.500.12390/2437


Título: Wound Healing Activity of an Ointment from Solanum tuberosum L. "Tumbay Yellow Potato" on Mus musculus Balb/c
Autor(es): Rosas-Cruz G.P. 
Silva-Correa C.R. 
Calderón-Peña A.A. 
Villarreal-La Torre V.E. 
Aspajo-Villalaz C.L. 
Cruzado-Razco J.L. 
Rosario-Chávarri J.D. 
Rodríguez-Soto J.C. 
Pretel-Sevillano O.E. 
Sagástegui-Guarniz W.A. 
González-Siccha A.D. 
Resumen: Background: Solanum tuberosum L. is an Andean tuber that is mainly characterized by its antioxidant properties. Objective: To evaluate the healing activity of an S. tuberosum-based ointment on wounds induced in mice. Material and methods: Ethanolic extracts of peel and pulp of tubers of S. tuberosum "Tumbay yellow potato"were prepared, which were incorporated into 1% and 2% ointment formulations. Mus musculus Balb/c with induced wound were distributed in the following working groups: Group I (Negative Control), Group II (Positive Control: Neomycin, Polymyxin B and Bacitracin Ointment) and Groups III and IV (Ointment at 1 % and 2% of S. tuberosum extract, respectively), daily administration of topical treatments were carried out for 07 days. Wound closure was determined during the experimentation time, then euthanized with sodium pentobarbital 60 mg/kg b.w. (i.p.) to obtain skin samples for histopathological analysis. Results: Groups III and IV showed that better evidence of wound closure and scarring in the histopathological analysis, the greatest effect being in Group IV. Conclusions: S. tuberosum ointments show healing activity in induced wounds in mice, the most effective treatment being the 2% ointment formulation. © 2020 Phcogj.Com.
Tema: Histology;Skin;Solanum tuberosum;Wound healing;Yellow potato
Editorial: EManuscript Technologies
Fecha de publicación: 2020
Publicado en: Pharmacognosy Journal 
Financiamiento: 115-2018-FONDECYT-BM-IADT-SE 
Tipo de publicación: info:eu-repo/semantics/article
Identificador Handle: http://hdl.handle.net/20.500.12390/2437
DOI: 10.5530/PJ.2020.12.175
Nivel de acceso: info:eu-repo/semantics/openAccess
Colección:6.1 Proyectos de investigación científica

Registro Dublin Core completo



Páginas vistas

3
marcado en 19-ene-2022

Google ScholarTM

Check

Altmetric

  • Compartir este item
  • QR Code

Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.