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Chemical composition by HPLC-ESI-QTOF-MS/MS: Estrogenic and antioxidant effects of Mangifera indica L. cv. "Kent" leave extracts on ovariectomized rats
Chemical composition by HPLC-ESI-QTOF-MS/MS: Estrogenic and antioxidant effects of Mangifera indica L. cv. "Kent" leave extracts on ovariectomized rats
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Fecha
2019
Autores
Benites, J
Asuncion-Alvarez, HD
Ybanez-Julca, RO
Ganoza-Yupanqui, ML
Jacinto-Fernandez, JJ
Reyes-De la Vega, JB
Zavaleta-Cruz, HJ
Pinedo-Alcantara, AN
Layado-Fonseca, CM
Medina-Mejia, CA
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Abstracto
The chemical composition of Mangifera indicaL. cv. "Kent" leaves was determined by HPLC-ESI-QTOF-MS/MS. Polyphenolic compounds characterized as benzophenone derivatives were the main components found in extracts and xanthones. The estrogenic and antioxidant effects of aqueous extracts from Mangifera indica L. cv. "Kent" leaves on ovariectomized rats were determined by uterotrophic assay and malondialdehyde (MDA) levels in erythrocytes, bone, liver, and stomach. We conclude that the polyphenolic compounds from extracts act as exogenous antioxidant agents against oxidative damage in ovariectomized rats.
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Fitoquímica,
Bioquímica