Publicación:
Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin

dc.contributor.author Gomes, C es_PE
dc.contributor.author Martinez-Puchol, S es_PE
dc.contributor.author Palma, N es_PE
dc.contributor.author Horna, G es_PE
dc.contributor.author Ruiz-Roldan, L es_PE
dc.contributor.author Pons, MJ es_PE
dc.contributor.author Ruiz, J es_PE
dc.date.accessioned 2024-05-30T23:13:38Z
dc.date.available 2024-05-30T23:13:38Z
dc.date.issued 2017
dc.description.abstract From its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Gram-positive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bacteria. Some of them, as azithromycin, are considered in the armamentarium against Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics to fight against Enterobacteriaceae infections. The present review is focused on the mechanisms of macrolide resistance, currently described in Enterobacteriaceae.
dc.description.sponsorship Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concytec
dc.identifier.doi https://doi.org/10.3109/1040841X.2015.1136261
dc.identifier.isi 391856800001
dc.identifier.uri https://hdl.handle.net/20.500.12390/1097
dc.language.iso eng
dc.publisher Society of Tropical Medicine and Hygiene
dc.relation.ispartof Critical Reviews in Microbiology
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject Mutaciones ribosomales
dc.subject ARNr 23S es_PE
dc.subject Metilasas es_PE
dc.subject Esterasas es_PE
dc.subject Fosfotransferasas es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.title Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
dc.type info:eu-repo/semantics/article
dspace.entity.type Publication
Archivos