Publicación:
Pyrrolizidine Alkaloids of Senecio sp from Peru
Pyrrolizidine Alkaloids of Senecio sp from Peru
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Fecha
2011
Autores
Vasquez, LR
Artiles, MR
Coloma, AG
Perez, RC
Mesia, LR
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Sociedade Brasileira de Quimica
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Abstracto
Six pyrrolizidine alkaloids (PAs) (two saturated macrocyclic, three unsaturated macrocyclic and one unsaturated seco-macrocyclic) were isolated from native Peruvian Senecio species. The structures of these alkaloids were established by a complete NMR spectroscopic analysis, chemical transformations and comparison of their NMR data with those published for similar alkaloids. Three PAs were then tested for antifungal activity against Fusarium moniliforme, F. (Sheldon), F. oxysporum fs. lycopersici (Scheldt) and F. solani (Mart), no significant activity being observed.
Descripción
This work was supported by a Collaborative Research Grant from CSIC-CONCYTEC, National University of the Peruvian Amazonia, Iquitos, Peru, Ministerio de Educacion y Ciencia, Spain (CTQ2009-14629-C02-01) and a predoctoral MAEC-AECID fellowship to L. R. Vasquez.
Palabras clave
Senecio,
19-acetoxisenkirkina,
alcaloides de pirrolizidina