Publicación:
Two complementary methods for the identification and production of novel biomarkers of Plasmodium falciparum
Two complementary methods for the identification and production of novel biomarkers of Plasmodium falciparum
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Fecha
2016
Autores
García Ruiz, Oscar Andree
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Universidad Peruana de Ciencias Aplicadas
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Abstracto
Ribosome profiling (RP) is a novel technique that exploits RNA sequencing and ribosome immobilization to quantify transcription and translation at different cell growth stages. Therefore, RP provides invaluable information for expression dynamics studies. Quantitative –omics studies are of crucial importance for identification of potential biomarkers of infection. An ideal parasite detection system should definitely establish the presence or absence of infection; determine the species involved; be detectable even in low concentrations; be proportional to parasite density; and determine the presence of antibiotic resistance.
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Palabras clave
Ribosome Profiling,
Genomics,
Gene Expression Profiling,
Biological Markers,
Malaria,
Plasmodium,
Medicina