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Cleavage and development in cultured preimplantation mouse embryos exposed to lidocaine
Cleavage and development in cultured preimplantation mouse embryos exposed to lidocaine
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Fecha
1996
Autores
Del Valle L.J.
Orihuela P.A.
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Elsevier
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Abstracto
Two-cell preimplantation mouse embryos were exposed in vitro to lidocaine (0 to 1,000 μg/mL) for 72 h to determine the effects of this anesthetic on subsequent cleavage and development during prolonged exposures. Embryonic development was monitored each 24 h for 3 d. Lidocaine adversely affected the in vitro development of the mouse embryos, altering the distribution of the development stages at the evaluated culture tunes.
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Acknowledgments -This investigationw as supportedb y a grant from the Sciences and Technology National Council (CONCYTEC, Project No 2043) Lima-Peru.
Palabras clave
Genética animal,
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